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{"patient":{"resourceType":"Patient","id":"NCT04793958-4","identifier":[{"use":"usual","system":"http://example.org/patients","value":"123456789"}],"name":[{"use":"official","family":"Jones","given":["Brian"]}],"telecom":[{"system":"phone","value":"555-123-4567","use":"home"},{"system":"email","value":"brian.jones@example.com","use":"home"}],"gender":"male","birthDate":"1970-05-15","address":[{"use":"home","line":["123 Main St"],"city":"Springfield","state":"IL","postalCode":"62701","country":"USA"}],"maritalStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/v3-MaritalStatus","code":"M","display":"Married"}]},"communication":[{"language":{"coding":[{"system":"urn:ietf:bcp:47","code":"en","display":"English"}]},"preferred":true}]},"fhirResources":[{"resourceType":"Condition","id":"NCT04793958-4-0","verificationStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/condition-ver-status","code":"confirmed"}]},"code":{"coding":[{"system":"http://snomed.info/sct","code":"363406005","display":"Malignant neoplasm of colon"}]},"subject":{"reference":"Patient/NCT04793958-4"}},{"resourceType":"Observation","id":"NCT04793958-4-1","code":{"coding":[{"system":"http://loinc.org","code":"33762-4","display":"KRAS gene mutation analysis"}]},"subject":{"reference":"Patient/NCT04793958-4"},"valueString":"KRAS G12C mutation"},{"resourceType":"MedicationStatement","id":"NCT04793958-4-2","status":"active","subject":{"reference":"Patient/NCT04793958-4"}},{"resourceType":"Procedure","id":"NCT04793958-4-3","code":{"coding":[{"system":"http://snomed.info/sct","code":"367336001","display":"Chemotherapy"}]},"subject":{"reference":"Patient/NCT04793958-4"}}],"patientNote":"Patient is a 53-year-old male with a history of colorectal carcinoma, confirmed to have a KRAS G12C mutation. He has previously undergone a fluoropyrimidine-based chemotherapy regimen with oxaliplatin. Recent imaging shows progression of the disease, indicating a need for second-line treatment. Patient denies any significant neurological symptoms, and there is no evidence of active brain metastasis. He has not received any prior treatment targeting the KRAS G12C mutation or anti-EGFR antibodies. Patient reports occasional abdominal discomfort but denies any severe pain or changes in bowel habits. He is currently managing well with his prescribed medications and maintains a good performance status. Blood work shows stable liver and kidney function. Patient is married and lives with his spouse, who is supportive and involved in his care. He is fluent in English and prefers to communicate in this language during medical consultations.","grade":"Disqualified"}

{"patient":{"resourceType":"Patient","id":"NCT04793958-3","identifier":[{"use":"usual","system":"http://example.org/patients","value":"123456789"}],"name":[{"use":"official","family":"Smith","given":["Amanda"]}],"telecom":[{"system":"phone","value":"555-123-4567","use":"home"},{"system":"email","value":"amanda.smith@example.com","use":"home"}],"gender":"female","birthDate":"1975-06-15","address":[{"use":"home","line":["123 Main St"],"city":"Springfield","state":"IL","postalCode":"62701","country":"USA"}],"maritalStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/v3-MaritalStatus","code":"M","display":"Married"}]},"communication":[{"language":{"coding":[{"system":"urn:ietf:bcp:47","code":"en","display":"English"}]},"preferred":true}]},"fhirResources":[{"resourceType":"Condition","id":"NCT04793958-3-0","verificationStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/condition-ver-status","code":"confirmed"}]},"code":{"coding":[{"system":"http://snomed.info/sct","code":"363406005","display":"Malignant neoplasm of colon"}]},"subject":{"reference":"Patient/NCT04793958-3"}},{"resourceType":"Observation","id":"NCT04793958-3-1","code":{"coding":[{"system":"http://loinc.org","code":"33762-4","display":"KRAS gene mutation analysis"}]},"subject":{"reference":"Patient/NCT04793958-3"},"valueString":"KRAS G12C mutation"},{"resourceType":"MedicationStatement","id":"NCT04793958-3-2","status":"active","subject":{"reference":"Patient/NCT04793958-3"}},{"resourceType":"Procedure","id":"NCT04793958-3-3","code":{"coding":[{"system":"http://snomed.info/sct","code":"367336001","display":"Chemotherapy"}]},"subject":{"reference":"Patient/NCT04793958-3"}}],"patientNote":"Patient is a 48-year-old female with a history of colorectal carcinoma, confirmed to have a KRAS G12C mutation. She has previously undergone a fluoropyrimidine-based chemotherapy regimen with oxaliplatin. Recent imaging shows progression of the disease. Patient reports experiencing increased abdominal pain and fatigue over the past few weeks. She denies any new neurological symptoms, and there is no evidence of active brain metastasis. Her past medical history includes hypertension, which is well-controlled with medication. She has not received any prior treatment targeting the KRAS G12C mutation, nor has she been treated with anti-EGFR antibodies. Patient is currently on a stable dose of antihypertensive medication and reports good adherence. She is married and lives with her spouse, who is supportive. The patient is fluent in English and prefers to communicate in this language. She is scheduled for follow-up imaging in three months to monitor disease progression.","grade":"Disqualified"}

{"patient":{"resourceType":"Patient","id":"NCT04793958-1","identifier":[{"use":"usual","system":"http://example.org/patients","value":"123456789"}],"name":[{"use":"official","family":"Jones","given":["Joseph"]}],"telecom":[{"system":"phone","value":"555-123-4567","use":"home"},{"system":"email","value":"joseph.jones@example.com","use":"home"}],"gender":"male","birthDate":"1965-07-15","address":[{"use":"home","line":["123 Main St"],"city":"Springfield","state":"IL","postalCode":"62701","country":"USA"}],"maritalStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/v3-MaritalStatus","code":"M","display":"Married"}]},"communication":[{"language":{"coding":[{"system":"urn:ietf:bcp:47","code":"en","display":"English"}]},"preferred":true}]},"fhirResources":[{"resourceType":"Condition","id":"NCT04793958-1-0","verificationStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/condition-ver-status","code":"confirmed"}]},"code":{"coding":[{"system":"http://snomed.info/sct","code":"363406005","display":"Malignant neoplasm of colon"}]},"subject":{"reference":"Patient/NCT04793958-1"}},{"resourceType":"Observation","id":"NCT04793958-1-1","code":{"coding":[{"system":"http://loinc.org","code":"33762-4","display":"KRAS gene mutation analysis"}]},"subject":{"reference":"Patient/NCT04793958-1"},"valueString":"KRAS G12C mutation"},{"resourceType":"MedicationStatement","id":"NCT04793958-1-2","status":"completed","subject":{"reference":"Patient/NCT04793958-1"}},{"resourceType":"Procedure","id":"NCT04793958-1-3","status":"completed","code":{"coding":[{"system":"http://snomed.info/sct","code":"367336001","display":"Colonoscopy"}]},"subject":{"reference":"Patient/NCT04793958-1"}}],"patientNote":"Patient is a 58-year-old male with a history of colorectal carcinoma, confirmed to have a KRAS G12C mutation. He has previously received first-line treatment with a fluoropyrimidine-based regimen including oxaliplatin. Recently, there has been radiographic evidence of disease progression. Patient reports experiencing increased abdominal pain and changes in bowel habits over the past few weeks. He denies any recent weight loss or changes in appetite. Past medical history is significant for hypertension and type 2 diabetes, both of which are well-controlled with medication. Patient has no known drug allergies. He has a history of receiving cetuximab in the past, which disqualifies him from certain treatment options. There is no evidence of active brain metastasis, but he has a history of migraines. Patient is currently on metformin and lisinopril. He is married and lives with his spouse, who is supportive. The patient is advised to continue monitoring symptoms and follow up with oncology for further management.","grade":"Qualified"}

{"patient":{"resourceType":"Patient","id":"NCT04793958-2","identifier":[{"use":"usual","system":"http://example.org/patients","value":"123456789"}],"name":[{"use":"official","family":"Davis","given":["Margaret"]}],"telecom":[{"system":"phone","value":"555-123-4567","use":"home"},{"system":"email","value":"margaret.davis@example.com","use":"home"}],"gender":"female","birthDate":"1965-07-15","address":[{"use":"home","line":["123 Main St"],"city":"Springfield","state":"IL","postalCode":"62701","country":"USA"}],"maritalStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/v3-MaritalStatus","code":"M","display":"Married"}]},"communication":[{"language":{"coding":[{"system":"urn:ietf:bcp:47","code":"en","display":"English"}]},"preferred":true}]},"fhirResources":[{"resourceType":"Condition","id":"NCT04793958-2-0","verificationStatus":{"coding":[{"system":"http://terminology.hl7.org/CodeSystem/condition-ver-status","code":"confirmed"}]},"code":{"coding":[{"system":"http://snomed.info/sct","code":"363406005","display":"Malignant neoplasm of colon"}]},"subject":{"reference":"Patient/NCT04793958-2"}},{"resourceType":"Observation","id":"NCT04793958-2-1","code":{"coding":[{"system":"http://loinc.org","code":"33762-4","display":"KRAS gene mutation analysis"}]},"subject":{"reference":"Patient/NCT04793958-2"},"valueString":"KRAS G12C mutation"},{"resourceType":"MedicationStatement","id":"NCT04793958-2-2","status":"active","subject":{"reference":"Patient/NCT04793958-2"}},{"resourceType":"Procedure","id":"NCT04793958-2-3","code":{"coding":[{"system":"http://snomed.info/sct","code":"387713003","display":"Chemotherapy"}]},"subject":{"reference":"Patient/NCT04793958-2"}}],"patientNote":"Patient is a 58-year-old female with a history of colorectal carcinoma, confirmed to have a KRAS G12C mutation. She has previously undergone a first-line treatment with a fluoropyrimidine-based chemotherapy regimen, including oxaliplatin. Recent imaging shows progression of the disease, indicating a need for second-line treatment. Patient denies any significant side effects from the previous chemotherapy, though she reports mild fatigue and occasional nausea. No history of treatment with anti-EGFR antibodies or therapies targeting KRAS G12C mutation. There is no evidence of active brain metastasis on recent MRI. Patient has a family history of colorectal cancer, with her mother diagnosed at age 65. She maintains a balanced diet and exercises regularly, though she has noticed a decrease in her energy levels. Blood pressure and other vital signs are within normal limits. Patient expresses concern about the progression of her disease and is eager to explore further treatment options. She is currently managing her symptoms with supportive care and is compliant with follow-up appointments.","grade":"Qualified"}

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Patient Settings